Tizanidine Hydrochloride

Tizanidine Hydrochloride is a short-acting muscle relaxant that works by blocking nerve impulses (pain sensations) sent to the brain. It acts as an alpha-2 adrenergic receptor agonist, reducing muscle spasms by slowing action in the spinal cord.

Dosage by Body Weight

Standard starting dose is 2 mg to 4 mg orally every 6 to 8 hours. Dosage can be adjusted gradually but should not exceed 36 mg in a 24-hour period. It is crucial to take it consistently either with food or without food, as food significantly affects drug absorption.

  1. Body Weight
    Below 5 kg
    Dose
    Not recommended
    Frequency
    Do not use
    Tracking Notes
    Safety and efficacy have not been established in pediatric patients.
  2. Body Weight
    5-7 kg
    Dose
    Not recommended
    Frequency
    Do not use
    Tracking Notes
    Safety and efficacy have not been established in pediatric patients.
  3. Body Weight
    8-10 kg
    Dose
    Not recommended
    Frequency
    Do not use
    Tracking Notes
    Safety and efficacy have not been established in pediatric patients.
  4. Body Weight
    11-15 kg
    Dose
    Not recommended
    Frequency
    Do not use
    Tracking Notes
    Safety and efficacy have not been established in pediatric patients.
  5. Body Weight
    16-20 kg
    Dose
    Not recommended
    Frequency
    Do not use
    Tracking Notes
    Safety and efficacy have not been established in pediatric patients.

Formulation

TabletCapsule

Purpose

Used to manage increased muscle tone (spasticity) associated with conditions such as multiple sclerosis, spinal cord injury, or chronic back pain.

Generic Name

Tizanidine Hydrochloride

Branded Drug Names

Tizanidine Hydrochloride is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:

Scheduled Drug

Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.

Alternatives

Disclaimer: This information is for educational purposes only. WHO references and weight bands are simplified for tracking and must not replace medical advice. Always consult with a healthcare professional before starting or changing any medication.